PGD – chromosomal translocation 2017-06-30T12:55:31+00:00

Pre-implantation genetic diagnosis – chromosomal translocation

For women experiencing repeated miscarriages and fertility problems due to chromosomal translocation, we offer pre-implantation genetic diagnosis to identify embryos that are free of chromosomal translocation.

A chromosomal translocation results when parts of two chromosomes have broken off from their original positions. They then switch each other’s places.

Usually, it is balanced as there is no missing or extra chromosome material. An individual who is a carrier of chromosome translocation can experience repeated miscarriages or fertility problems.

To help those couples, we can offer PGD to identify embryos that are free of such translocation. This can happen after either one of them have been identified to be carrier of chromosome translocation.

Couples considering such a treatment will undergo an IVF or ICSI treatment. They will be given medications to stimulate ovaries to produce multiple eggs.

When the eggs are considered to be mature, patients undergo egg collection under sedation. The eggs will be fertilised either by IVF or injected with each sperm (ICSI).

A few cells will be removed from each viable embryo at blastocyst stage (day-5). We test them for chromosomal translocation and the embryo that is considered free of such translocation will be replaced.

microbiological pipette

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